Protein Fluorescence Database
نویسندگان
چکیده
The fluorescence properties of tryptophan residues are sensitive to the microenvironment of tryptophan fluorophores in proteins. Therefore, fluorescence characteristics are widely used to study structural transitions in proteins. We have developed algorithms for the decomposition of multi-component protein fluorescence spectra and the correlation of these spectral parameters with protein structural properties, which are available via PFAST (Protein Fluorescence And Structural Toolkit, http://pfast.phys.uri.edu/). We then applied these algorithms for the analysis of fluorescence properties of more than 300 proteins and created the first database of protein fluorescence properties, which is available on the PFAST website (http://pfast.phys.uri.edu/database/database.php).
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تاریخ انتشار 2011